dc.contributor.advisor | Camacho Kurmen, Judith Elena | |
dc.contributor.author | Ortegón Orduña, Juanita | |
dc.contributor.author | Zuluaga Echeverri, Luz Yerly | |
dc.date.accessioned | 2024-05-23T17:29:55Z | |
dc.date.available | 2024-05-23T17:29:55Z | |
dc.date.issued | 2022-04 | |
dc.identifier.uri | https://repositorio.unicolmayor.edu.co/handle/unicolmayor/6912 | |
dc.description.abstract | La depresión es un trastorno caracterizado por la presencia de tristeza, pérdida de interés,
sentimientos de culpa; se puede clasificar como leve, moderada o grave. El presente trabajo
se centra en la influencia de los inhibidores selectivos de la recaptación de serotonina (ISRS)
en la microbiota intestinal de las personas con depresión. Se basa en el eje intestino-cerebro
que consiste en una red de comunicación que monitorea e integra las funciones intestinales y
las vincula a los centros cognitivos y emocionales del cerebro. Esta investigación se lleva a
cabo por una revisión bibliográfica y un análisis bibliométrico, donde se explica el eje, se
analiza el impacto en la microbiota con el uso de antidepresivos, se describe el efecto de
estos en pacientes con depresión y se indagan los tratamientos adicionales que pueden ser
utilizados. Los ISRS son medicamentos de primera línea, estos inhiben los transportadores de
serotonina aumentando los niveles de 5-hidroxitriptamina, la concentración prolongada de
estos en la luz intestinal afectan la microbiota generando disbiosis, la cual se puede prevenir
con el uso de probióticos, prebióticos, psicobióticos o dieta. Como conclusión los ISRS
poseen acción antimicrobiana, el tratamiento más prometedor es el uso de probióticos por el
gran beneficio que conlleva en el intestino. A nivel nacional pese al desarrollo de una Política
Pública de Salud Mental no se cuenta con la cobertura adecuada se dificulta el acceso a los
servicios y tratamientos incompletos; por lo que se sugiere seguir investigando sobre el tema
y en planes de prevención. | spa |
dc.description.tableofcontents | TABLA DE CONTENIDO
RESUMEN 6
INTRODUCCIÓN 8
1. ANTECEDENTES 10
2. MARCO REFERENCIAL 16
3. DISEÑO METODOLÓGICO 27
3.1. Universo, población y muestra 27
3.2. Hipótesis, variables, indicadores 27
3.3. Técnicas, procedimientos 28
4. RESULTADOS Y DISCUSIÓN 29
5. CONCLUSIONES 36
6. REFERENCIAS BIBLIOGRÁFICAS 37
7. ANEXOS 51 | spa |
dc.format.extent | 105p. | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | spa | spa |
dc.publisher | Universidad Colegio Mayor de Cundinamarca | spa |
dc.rights | Derechos Reservados - Universidad Colegio Mayor de Cundinamarca, 2024 | spa |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | spa |
dc.title | Influencia de los inhibidores selectivos de recaptación de serotonina en la microbiota intestinal de personas con depresión | spa |
dc.type | Trabajo de grado - Pregrado | spa |
dc.contributor.corporatename | Universidad Colegio Mayor de Cundinamarca | spa |
dc.description.degreelevel | Pregrado | spa |
dc.description.degreename | Bacteriólogo(a) y Laboratorista Clínico | spa |
dc.publisher.faculty | Facultad de Ciencias de la Salud | spa |
dc.publisher.place | Bogotá D.C. | spa |
dc.publisher.program | Bacteriología y Laboratorio Clínico | spa |
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dc.rights.accessrights | info:eu-repo/semantics/closedAccess | spa |
dc.rights.creativecommons | Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) | spa |
dc.subject.proposal | Depresión | spa |
dc.subject.proposal | Microbiota intestinal | spa |
dc.subject.proposal | Inhibidores Selectivos de la Recaptación de Serotonina (ISRS) | spa |
dc.subject.proposal | Disbiosis intestinal | spa |
dc.subject.proposal | Tratamiento | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_7a1f | spa |
dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
dc.type.content | Text | spa |
dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
dc.type.redcol | https://purl.org/redcol/resource_type/TP | spa |
dc.type.version | info:eu-repo/semantics/publishedVersion | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_14cb | spa |